Pick your course strategically.
With your race goal and distance selected, think about where you want to run. Do your best to avoid obstacles like heavy traffic, construction areas, stop lights and crowds. Flatter is faster, making tracks and greenways ideal for PRs. Trails are often quieter and more secluded (just make sure that the area in which you want to run is open).
It’s also important to consider logistics. Will you be running from home? Driving somewhere? If you need to pee, where will you go?
With a multi-loop course or an out and back, logistics are simple. You can focus on your pace without spending energy on navigation. You can also create your own aid stations that you can pass more than once, such as your own hydration and nutrition station or a discreet place to use the bathroom (alternatively, carry hydration with you on the run). This could be as simple as running by your car to grab a gel or looping by a wooded area for a pit stop.
If you run point-to-point, make plans with a member of your household to pick you up at the end of the course. This person can also serve as your crew. Arrange a meeting spot to refill your water along the way and they can cheer you on to your big finish.